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Can you take Florastor and Culturelle together?

By Cara Orlan, Registered Dietitian

If you're someone who suffers from digestive issues, you may have come across the popular probiotics Florastor and Culturelle.

These two supplements are designed to promote gut health and restore balance to your microbiome, but can they be taken together?

florastor vs culturelle
florastor vs culturelle

Can you take Florastor and Culturelle together?

The short answer is that it's generally safe to take Florastor and Culturelle together.

Both supplements contain different strains of probiotics, and there's no evidence to suggest that combining them would be harmful.

Florastor probiotic

Florastor contains a probiotic strain of yeast called Saccharomyces boulardii, which has been shown to be effective in treating various gastrointestinal disorders, including diarrhea and inflammatory bowel disease.

Culurelle probiotic

Culturelle, on the other hand, contains Lactobacillus rhamnosus GG, which has been shown to improve immune function and reduce the incidence of respiratory infections.

While both supplements contain different strains of probiotics, they work in different ways to promote gut health.

Does Florastor really work?

Florastor is a probiotic supplement containing Saccharomyces boulardii. It has been studied for digestive health and may help manage conditions like diarrhea and IBS.

While effectiveness can vary, Florastor is generally well-tolerated and has shown benefits for some individuals. Consult a healthcare professional for personalized advice.

Florastor is particularly effective at restoring balance to the gut flora after an infection or course of antibiotics, while Culturelle is better suited for maintaining overall gut health and promoting immune function.

Can I take florastor with other probiotics

It is generally safe to take Florastor with other probiotics, but it's always best to consult with a healthcare professional before combining different supplements. They can provide personalized advice based on your specific health needs and any potential interactions between different probiotic products.

That being said, there are a few things to keep in mind if you decide to take Florastor and Culturelle together.

First, it's important to start with a low dose of each supplement and gradually increase as needed. This will help your body adjust to the new strains of probiotics and minimize any potential side effects.

Additionally, it's important to speak with your healthcare provider before starting any new supplement regimen, especially if you have a history of digestive issues or other health concerns. They can help you determine the best course of action based on your individual needs and medical history.

Can you take Florastor and Culturelle together?
Can you take Florastor and Culturelle together?

Does florastor help with constipation

Florastor is primarily known for its effectiveness in supporting digestive health and promoting a healthy balance of gut bacteria.

While it may indirectly contribute to improved bowel movements for some individuals, it is not specifically indicated or marketed as a treatment for constipation.

If you are experiencing constipation, it's advisable to consult with a healthcare professional who can recommend appropriate interventions and discuss potential options for relief.

Florastor weight loss

Florastor is not specifically designed or marketed as a weight loss product. It is a probiotic supplement that is primarily used to support digestive health and promote a healthy balance of gut bacteria.

While maintaining a healthy gut microbiome can indirectly contribute to overall well-being, including potential benefits for weight management, it is important to note that individual results may vary.

If you are seeking to lose weight, it is advisable to focus on a comprehensive approach that includes a balanced diet, regular physical activity, and consultation with a healthcare professional or a registered dietitian for personalized guidance.

Davie Nutritionist
Davie Nutritionist

My top pick for a Probiotic is....

FloraMend Prime Probiotic From Thorne

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A healthy gut is key to overall wellness. Digestive health, immune function, and the state of your mood are dependent on the health of your gut and its microbiome. Support your gut health and much more with Thorne’s FloraMend Prime Probiotic.*

FloraMend offers benefits for occasional digestive upset, nutritional support for a challenged immune system, and balanced gut flora for healthy neurotransmitter production – important for a positive mood and healthy outlook.* A unique benefit of FloraMend Prime evidenced based probiotic is the research on this proprietary blend’s benefit for weight management.* Who can benefit from FloraMend Prime Probiotic?

  • Individuals wanting to improve weight management, waist circumference, or body mass index (BMI)*

  • An individual experiencing occasional diarrhea, constipation, or both*

  • Anyone looking to support their immune function, including individuals suffering from a seasonal allergy*

  • Everyone! Anyone can benefit from a healthy balance of gut flora*

What makes FloraMend Prime Probiotic different? Clinically studied for weight management Most probiotics will support balanced gut flora, digestive function, and a healthy immune response. But FloraMend Prime Probiotic’s proprietary blend boasts the added benefit of proven weight management support.* A study on the ingredients in FloraMend showed a nearly 5-percent average reduction in visceral and subcutaneous body fat with correlating positive effects on body weight, waist circumference, and BMI.* Activity where it matters most in the gut Probiotic supplements, by definition, contain live bacteria. These bacteria can be sensitive to the acid in your stomach, which can damage the bacteria before it gets to where it matters most – your lower GI tract. FloraMend Prime Probiotic is delivered in an acid-resistant and moisture-resistant capsule, which ensures that the live bacteria will make it past your stomach and into your lower GI tract, where it belongs.* No refrigeration needed The proprietary strains in FloraMend are stable at room temperature. FloraMend delivers the five billion live cells stated on the label up to the date of expiration. This makes FloraMend a great probiotic option for travel, the office, or simply keeping it from getting lost in the fridge.

Dietitian Cara Axelrod Orlan
Dietitian Cara Axelrod Orlan


Culturelle vs align vs florastor

  • Culturelle:

  • Contains the probiotic strain Lactobacillus rhamnosus GG.

  • Supports overall digestive health and immune function.

  • Helps maintain a healthy balance of gut bacteria.

  • May help with occasional digestive upset, such as bloating or gas.

  • Available in different formulations, including capsules, chewables, and powders.

  • Align:

  • Contains the probiotic strain Bifidobacterium infantis 35624.

  • Supports a healthy digestive system and helps promote regular bowel movements.

  • Helps soothe and manage digestive discomfort, such as abdominal discomfort and urgency.

  • Clinically proven to provide digestive balance and relieve occasional digestive upsets.

  • Available in capsules and chewables.

  • Florastor:

  • Contains the probiotic strain Saccharomyces boulardii lyo.

  • Helps promote digestive health and restore natural balance in the gut.

  • Supports the body's natural defense against digestive imbalances.

  • Clinically proven to help reduce the frequency and duration of diarrhea.

  • Suitable for adults and children, and can be taken with antibiotics.

It's important to note that individual responses to probiotics may vary, and the choice between these products may depend on personal preferences, specific health concerns, and guidance from a healthcare professional.


In conclusion, taking Florastor and Culturelle together is generally safe and may even provide additional benefits for your gut health. However, it's important to start with a low dose and speak with your healthcare provider before beginning any new supplement regimen.

Can you take Florastor and Culturelle together?

The short answer is that it's generally safe to take Florastor and Culturelle together.

Can you take Florastor and Culturelle together?
Can you take Florastor and Culturelle together?

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About Cara Orlan

Registered Dietitian Nutritionist

She is the founder of Your Dietitian For Life LLC, and is a highly respected registered dietitian nutritionist specializing in personalized nutrition for stress-free weight loss. With a remarkable portfolio of over 50 published peer-reviewed articles, Cara has established herself as a leading professional in her field.


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